Fixation on Histology Blog

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Fixation on Histology, NSH’s blog, features quick, easy to read articles on all aspects of the histotechnology field. Learn about techniques, troubleshooting tips, staining methods, laboratory safety, immunohistochemistry, management, inspections, and more, when you subscribe!

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Barcoding was developed to reduce manual data entry and errors that can occur as a result of manual work. ...
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Analysis of costs of clinical laboratory tests is as important as the quality indicators of the laboratory ...
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According to Elon Musk, the four most important traits that are critical for building a great team are: ...
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We know that Immunohistochemistry is the combination of three distinct fields—histology/pathology, immunology, ...
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Let’s face it. It’s a fast-paced world. It’s been reported that the average human makes 35,000 choices ...
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So you have spent time searching, screening and have a number of articles that you want to gather . However, ...
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Many early career scientists struggle with the task of screening, reading and collecting biomedical literature.   ...
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There are many sayings involving time. Time flies. Time is money. Time heals all wounds. But we know ...
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“ Open access ”, the ability to access biomedical literature free of charge and with few restrictions, ...
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Reading the biomedical research literature can be a time-consuming and intimidating task, especially ...
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Drying slides in a microwave presents itself as a faster alternative to the traditional oven, but academic ...
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As a laboratory safety consultant, I have billed myself as “the Superhero of Lab Safety.” I did that ...
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ISO 9000, ISO 15189, CAP 15189, and GHS – that is a lot of acronyms! Whether you are new to the lab environment ...
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By Amy Lynn Aulthouse, Ph.D., Professor, Biological and Allied Health Sciences, Ohio Northern University, ...
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Self-awareness is a management buzzword that we hear all the time.  But what does it really mean to be ...
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Scientific progress is dependent upon solving complex problems and creating innovative solutions. When ...
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There are different factors that negatively affect the quality of samples in the histology laboratory ...
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This article is designed to help you with working with recruiters.  There are a lot of recruiting firms ...
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The Giemsa stain is one of several hematology stains known as Romanowsky Stains which differentiate various ...
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Proper ventilation is required in histology laboratories to reduce the possibility of exposure to chemicals ...
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H&E staining is not able to specifically distinguish melanin from surrounding tissue, which is why ...
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Malignant melanoma (MM) remains the deadliest form of skin cancer. The current advances in patient cancer ...
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In a recent post we talked about Congo red , an amyloid stain with a pretty fascinating history, but ...
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The Journal of Histotechnology is the official industry journal of the National Society of Histotechnology. ...
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Amyloids are proteins that gather to form deposits in organs such as the liver or kidneys but are commonly ...
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Many people, not just histologists, have a morbid curiosity when it comes to medical oddities. This fascination ...
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Ten years ago, at 5.17pm on the evening of Sunday 22nd May 2011, the National Weather Service issued ...
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Why even bother to learn about troubleshooting? Wouldn’t it be more interesting to listen to one of the ...
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In a recent post , we talked about the Alcian Blue and Mucicarmine stains, which are both used for mucins, ...
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Bone marrow biopsies/aspirates are unique specimens in that a portion of each sample is sent to four ...
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Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis. It typically affects ...
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The histotechnologist plays a vital role in specimen processing from start to finish, and you may find ...
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There are several histology stains, such as Ziehl-Neelsen, that demonstrate acid fast bacteria. Acid ...
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Cryo-fluorescence tomography is an imaging modality that aims to bridge the gap between in vivo and ex ...
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Max Bielschowsky was a German neuropathologist at the beginning of the 20th century. Most of his life’s ...
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You may have heard the term companion diagnostic, but what actually is it, and how do companion diagnostics ...
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With the growth of immunotherapies, identifying biomarkers has become increasingly important. Traditionally, ...
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Like many of the other dyes currently used in histology, Alcian blue started out in the textile industry, ...
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PD-L1 or programmed death-ligand 1 is expressed as a transmembrane protein, which on regular cells, binds ...
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In 2015, as part of fulfilling my MSc degree, I completed a study, “Status of Histopathology Services ...
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As the world shut down during the COVID-19 pandemic, many organizations have had to adapt the way they ...
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Cancer diagnosis and accurate selection of an appropriate treatment are an important result of a histologist’s ...
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A lot has changed in the past year for all of us in many ways. That includes how we manage our careers, ...
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In next week’s post we are going to talk about immunotherapy, specifically adoptive cell transfer (ACT), ...
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Melanoma, though not the most common type of skin cancer, is extremely dangerous if not caught early ...
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In our last post , we discussed the regulations that OSHA sets for laboratories to create and maintain ...
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In this two-part blog post series, we will cover the requirements for OSHA and CAP when it comes to creating ...
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Christine Carreira is a Research Assistant working in the WHO/IARC Classification of Tumours Group (WCT) ...
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Histotechnologists work on all types of tissue depending on the type of lab they work in and it is not ...
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NSH recently opened abstract submissions for our 47th Annual Convention, taking place virtually September ...
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Validation and optimization; both are important processes in histology, but they are not the same thing ...
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In immunohistochemistry, labeling refers to adding a “tag” to an antibody to aid in detection. There ...
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The College of American Pathology (CAP) is one of the accrediting bodies that ensures histology labs ...
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Efficient and reliable laboratory services are essential to a functioning health system as quality laboratory ...
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This is the fourth iteration of the COVID survey. It received 364 responses. This is compared to 704 ...
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It is with great sadness that we share the news that Mrs. Hazel Dalton has passed away. Mrs. Dalton was ...
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After you have successfully pre-treated your IHC sample, it may be required to complete a blocking step. ...
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The new year is upon us (thank goodness!) and many of us are hoping for a very different year. Do we ...
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Formaldehyde, diluted down to the solution we know in histology as formalin, has been a popular fixative ...
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After 40 years of no fine increases, the United States Occupational Safety and Health Administration ...
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The NSH Board of Directors signed on to a coalition letter to the Centers for Disease Control and Prevention ...
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Though a national certification for histotechnology is not required to work in the field, there are several ...
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CPT stands for Current Procedural Terminology. CPT codes are service codes that identify medical procedures. ...
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Electron microscopes use electrons as opposed to light to produce an image of the specimen being observed. ...
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Ergonomics is commonly defined as fitting the job or equipment used on the job, to the worker. It is ...
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Formalin fixation is essential for preserving the morphology of tissue, but formalin fixation is also ...
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Billie Strode Swisher….a dear friend, a colleague, an educator, a great mentor, a long successful career! ...
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Andi Grantham…Ken Urban…Lena Spencer…Billie Swisher These are some of the people we lost this year… ...
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Having an efficient tissue processing protocol is crucial for multiple reasons. With its upstream position ...
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We’re very happy to be ringing in 2021 and wanted to close out 2020 by sharing some of the highlights ...
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ASCP has recently published the results from their 2019 wage survey, the biannual evaluation of salaries ...
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Lena was a good friend and mentor to me for many years. I met her over 30 years ago when she was the ...
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No greater name stands alone in biology than that of Charles Robert Darwin. Born in Shrewsbury, England ...
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“What is glyoxal?” If you ask most histotechnologists, they will look at you blankly, unless, of course, ...
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As you know if you’ve read our previous post on regulatory agencies for the histology lab , OSHA is ...
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If you are planning on taking the HTL exam, you will need to be familiar with enzyme histochemistry. ...
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Immunohistochemistry and immunofluorescence are today becoming routine and a necessity for pathology ...
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While patient care is still the primary goal of any histology lab, efficiency has increasingly become ...
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Histology labs have a pretty large environmental footprint, from the water we consume, to the waste we ...
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If you work in a CAP accredited laboratory you must be able to demonstrate competency for any individuals ...
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Like many before me I had an eclectic route to histology by meandering my way through jobs that provided ...
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Hiring a histology professional presents a unique set of challenges like the ongoing shortage of qualified ...
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Many stressors plague us in the laboratory, with some leading to burnout, but there is hope in reducing ...
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The concept behind silver staining, the recognition that silver nitrate can stain organic substances, ...
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Regulatory bodies exist to ensure both the safety of the personnel working in the laboratory, as well ...
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Histology is full of negotiations, whether you’re negotiating with your boss for a better salary or negotiating ...
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Histotech of the Decade, Sponsored by Epredia: Lena Spencer Lena Spencer has played an active ...
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In my time of reflection in the past few days concerning the passing of my dear friend Ken Urban, I had ...
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When the Coronavirus hit this past Spring, histologists were understandably curious whether additional ...
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Nuclear bubbling in histology refers to when nuclear detail is lost and nuclei appear “smudgy”, for lack ...
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Every office has that colleague who leaves their food in the fridge, or cup on their desk, a little too ...
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Aldehydes The most common type of fixative used in histology is aldehydes. Aldehydes are compounds ...
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Generally speaking, there are only two methods employed for identifying antigens with a fluorescent dye; ...
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Humans have long understood the powerful pull of curiosity—in proverb and myth, curiosity kills the cat ...
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Change can be scary, but sometimes when it comes to the processes in our laboratory, change can make ...
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Quality control and consistent reproducibility of results in staining is essential for accurate diagnosis. ...
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Fire is very much in the news these days, as large portions of America’s West Coast are engulfed in devastating ...
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Though based in the United States, NSH is an international organization with many members in countries ...
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On Sept 11, 2001, a traumatic incident left an indelible mark on society and all of the lives that were ...
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You’re in charge of interviewing a potential new hire for your laboratory. You want to make sure that ...
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“Founded on pioneer research, supported by rare skill in execution, inspired by the highest ideals, this ...
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Like pretty much everyone else, NSH has had to make a lot of changes and adjustments this year due to ...
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Ocular pathology is a broad discipline that not only involves diagnostic or post-mortem evaluations; ...
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The third iteration of NSH’s COVID-19 Survey received fewer responses than the first two surveys, closing ...
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I decided to attend the NSH 46th Annual Virtual Symposium/Convention in the hopes of further growth ...
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Recently, I selected some immunohistochemistry cases from file to photograph, and I realized that some ...
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Histology often makes use of some unusual products you wouldn’t normally think of as laboratory materials. ...
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For most dog owners, the quality of the food, toys, chews, and treats their canine best friends put in ...
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According to the Skin Cancer Foundation, Mohs surgery is considered the most effective technique for ...
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Carnoy’s solution is one of the older fixatives you’ll find in histology, with first publication in the ...
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A few weeks ago we asked some of our histology students to write about how COVID has impacted their histology ...
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Hazardous waste is a popular topic here on Fixation on Histology. We’ve had posts covering the difference ...
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A quick introduction about myself: My name is Chanda Renee Harris. I graduated with a Bachelor’s Degree ...
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I have been asked the same question many times these past few months; what is the job outlook for histology? ...
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FISH is a technique that uses a fluorescent labeled probe that attaches to a complementary DNA sequence ...
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You hear from me every year (whether you realize it or not) about why attending a face-to-face meeting ...
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In order to balance the requirements for the Credential Maintenance Program (CMP) across all technologist ...
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Today’s post is all about jars, specifically the jars you encounter every day in your histology lab. ...
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NSH asked our student members to share their experiences during COVID-19. How has COVID-19 impacted their ...
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Over the last 50 years, the histology laboratory has witnessed countless technological advances in the ...
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Apoptosis put very simply is cellular suicide. It is the natural process the cells in your body undergo ...
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In May, NSH started a survey project with the aim of determining how COVID-19 had impacted employment ...
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Fixation is an essential step in the histology process that preserves the tissue and makes the tissue ...
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Special stains are performed when there is something that is not adequately visualized with an H&E ...
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CAP, or the College of American Pathologists, is an accrediting body for laboratories. Their inspections ...
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On May 11, 2020 NSH published a survey to our histology community asking them to answer a few questions, ...
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Monday is Memorial Day, a day in the United States dedicated to honoring our veterans. Many within the ...
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At embedding many histotechs think it's best to, "squeeze out the fat" in order to cut the perfect section. ...
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The H&E stain is often described as the histologist’s bread and butter stain, as it is used so often ...
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It has been nearly two months since the COVID-19 pandemic hit the US in full force, and histology labs ...
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In today’s post we will confront some of the common microtomy problems you could run into, and what you ...
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A little history! My first day in the histology lab, was November 7, 1960. I was so enamored with the ...
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We get a lot of questions about control tissue on The Block , NSH’s member community, and our Facebook ...
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Tomorrow, Wednesday April 22nd is Earth Day and while all of the social distancing measures put into ...
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If you had a crystal ball, what would your prediction be for the future of histology? That is the question ...
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