Types of Silver Stains

By Natalie Paskoski posted 11-05-2020 14:35

The concept behind silver staining, the recognition that silver nitrate can stain organic substances, dates back to the 12th century, but it wasn’t until the mid-late 19th century that silver nitrate becomes more widely used in science. It is around this time that silver nitrate is utilized in photographic development and it slowly is tested for use in histological staining. By the 1970’s, Kerenyi and Gallyas, generally credited with the origin of the silver stain, begin using it from observation of proteins in gels. Camillo Golgi is generally credited with adapting silver staining for use in the central nervous system. Continue Reading