Presented by: Kimberly Feaster, HTL(ASCP)QIHC,West Virginia University, Morgantown, WV
Standardization is a continual challenge in immunohistochemical
testing. When considering the various parameters involved (i.e. tissue acquisition, fixation, protocol steps, reagents, instrumentation), this is not surprising; however, consistency and
reproducibility are more important than ever. The prominence of personalized medicine, particularly companion diagnostics, has increased clinical accessibility to antibodies capable of identifying
mutated or abnormally expressed proteins which are then targeted by therapeutic drugs. Consistency and reproducibility are also important in research in order to validate antibodies and their
results. Aside from understanding the significance, the process and approach to standardization can be overwhelming. In the 1990s, a more rigorous ‘Total Test’ approach was recommended for IHC
assays. This approach offers a comprehensive, methodical review by categorizing the factors that affect consistency and reproducibility. This session will explore the challenges to standardization
factored into the approach, and how it can be utilized to improve standardization in any laboratory setting.
This webinar is part of the 2020 Laboratory Webinar Series.
Laboratory Webinars are a great, inexpensive way to provide continuing education to a large number of employees.
The cost for each session is the same regardless of the number
*Earn CEU's - One CEU per attendee per session
*Group Learning - Unlimited # of participants for one low fee
*Archive Sessions - Archived
materials are available for 1 year to train new staff - AND STILL EARN CEUs!
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