The Total Test Approach to IHC Standardization

When:  Jul 22, 2020

Presented by: Kimberly Feaster, HTL(ASCP)QIHC,West Virginia University, Morgantown, WV

Standardization is a continual challenge in immunohistochemical testing. When considering the various parameters involved (i.e. tissue acquisition, fixation, protocol steps, reagents, instrumentation), this is not surprising; however, consistency and reproducibility are more important than ever. The prominence of personalized medicine, particularly companion diagnostics, has increased clinical accessibility to antibodies capable of identifying mutated or abnormally expressed proteins which are then targeted by therapeutic drugs. Consistency and reproducibility are also important in research in order to validate antibodies and their results. Aside from understanding the significance, the process and approach to standardization can be overwhelming. In the 1990s, a more rigorous ‘Total Test’ approach was recommended for IHC assays. This approach offers a comprehensive, methodical review by categorizing the factors that affect consistency and reproducibility. This session will explore the challenges to standardization factored into the approach, and how it can be utilized to improve standardization in any laboratory setting.


This webinar is part of the 2020 Laboratory Webinar Series.
Laboratory Webinars are a great, inexpensive way to provide continuing education to a large number of employees.
The cost for each session is the same regardless of the number of attendees.

*Earn CEU's - One CEU per attendee per session
*Group Learning - Unlimited # of participants for one low fee
*Archive Sessions - Archived materials are available for 1 year to train new staff - AND STILL EARN CEUs!

Please note you may not use the purchased login information at multiple locations of your organization.
Only one site may use the login for the live event. If you have additional sites interested in a webinar, they must register.
NSH offers group/multisite discounts. Contact Connie Wildeman, connie@nsh.org for group discount details.

Any questions please contact the NSH Office, 443-535-4060 or histo@nsh.org.